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Selank’s mechanism of action is suspected to be related to the increase of serotonin. Serotonin influence’s appetite, supports a positive mood, and regulates the sleep and wake cycle. It is also well established that a serotonin deficient state can lead to depression, difficulty sleeping, and lack of an appetite.
A study on mice to unveil the effects of selank on neurotransmitter monomines and their metabolites showed significant differences in the content of dopamine, serotonin, norepinephrine, and in the levels of their hypothalamus, hippocampus, and frontal cortex. Further research supports selank’s serotonin raising ability.